2010 MSG Annual Meeting

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The Muscle Study Group held its annual meeting on September 20-22, 2010 at Beaver Hollow Conference Center, Java Center, NY.

The agenda included five major sessions: The Challenges of Patient Recruitment, Recruiting the Next Generation of NMD Investigators, Inflammatory Myopathies: Pathogenesis, Treatment and Clinical Trials, Inflammatory Myopathies: Pathogenesis, Treatment and Clinical Trials (Continued), and Past, Current and Future Protocols: Lessons Learned.

The meeting was sponsored by:

  • National Institutes of Health, Grant #1R13NS071695-01:
    • National Institute of Neurological Disorders and Stroke (NINDS)
    • Office of the Director (OD)
    • National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
  • Muscular Dystrophy Association
  • ISIS Pharmaceuticals
  • PTC Therapeutics

Presentations

The Muscle Study Group received permission to post these presentations online:

Myositis Patient RegistryBob Goldberg

FOR-DMD Steroid TrialRobert Griggs

European Perspective on RecruitmentMichael Hanna

Update from British Myology SocietyMichael Hanna

Young Neurologists in the Basic LibraryAhmet Hoke

NIH Report on Support for Research on Neuromuscular DiseasesGlen Nuckolls

IMACS History and DevelopmentChester Oddis

Abstracts

The Muscle Study Group received permission to post the following abstracts online:

Safety and Feasibility of Transvenous Limb Profusion with Saline in Human Muscular DystrophyJames Howard

Mechanism of Axonal Degeneration in Drosophilia Model of Distal SBMAThomas Lloyd

Reproductability and Reliability of Quantitative MRI Measures for Neuromuscular DiseaseJasper Morrow

Clinical Improvement and Decreased Peripheral Autoreactivity in Refractory Myasthenia Gravis Treated with RituximabRichard Nowak

A Therapy for Duchenne Dystrophy Based Upon Inhibition of Mechanically Sensitive Ion ChannelsFrederick Sachs

Inherited Neuropathies ConsortiumCarly Siskind


2009 MSG Annual Meeting

The MSG held its annual meeting on September 21-23, 2009 at Beaver Hollow, Java Center, NY.

The meeting, entitled “Fostering Pharma-Academic Partnerships in Neuromuscular Experimental Therapeutics,” brought together members of the pharmaceutical industry and academic researchers.

The agenda included two major sessions: (1) Novel designs and outcome measures in translational neuromuscular research and (2) scientific updates in basic science, methods and treatment strategies.

The meeting was sponsored by:

  • National Institutes of Health:
    • National Institute of Neurological Disorders and Stroke (NINDS)
    • Office of the Director (OD)
    • National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
  • Muscular Dystrophy Association
  • ISIS Pharmaceuticals
  • PTC Therapeutics
  • Santhera Pharmaceuticals

Presentations

The MSG received permission to post these presentations online:

The Peripheral Nerve Study Group – Its Rise and DemiseArthur Asbury

Treatment of Neuromuscular Diseases With Antisense OligonucleotidesFrank Bennett

FOR-DMDKate Bushby

MSG – Past, Present, FutureRobert Griggs

HYP-HOP Robert Griggs

The SMA ProjectJill Heemskerk

High Dose Vitamin C Treatment of CMT CMT-1ARichard Lewis

Dermal Nerve Assessment: A Window to the Mechanism of Neuropathies in Outcome MeasuresJun Li

The Challenges of Conducting Clinical Development in Rare/Orphan Diseases: The Industry PerspectiveThomas Meier

Attaining Symbiosis in Therapy Development Efforts in NMDsJohn Porter

Trial Design and Outcomes for Inherited Neuropathy NetworkDavide Pareyson

Abstracts

The MSG received permission to post the following abstracts online:

TREAT-NMD and the ICC: A Fruitful Collaboration to Foster Clinical Trials and Research in SMAAnna Ambrosini

Using Video Gait Analysis to Assess Gait Dysfunction in Duchenne Muscular Dystrophy: A Pilot StudyYaacov Anziska

Use of the 6-Minute Walk Test to Assess Potential Drug Effects of Ataluren (PTC124) in Duchenne/Becker Muscular DystrophyLeone Atkinson

Mechanostat theory used to understand bone complications in children with Duchenne muscular dystrophyCraig Campbell

Sparing of Myofiber Membranes in Infantile Pompe’s DiseaseLudwig Gutman

Clinical Development of idebenone (CATENA) for the treatment of Duchenne Muscular Dystrophy – A summary of Phase II study results and design of a Phase III clinical studyThomas Meier

The challenges of conducting clinical development in rare/orphan diseases – The industry perspectiveThomas Meier

Diagnosis of Pompe Disease: Timing and Methods Used as Reported to the Pompe RegistryTim Miller

Fatty Acid Oxidation Disorders in Adults: A potentially treatable case of muscle diseaseRobert Pitceathly

Presence and Nature of “Tau” Immunoreactivity in Normal Myonuclei and Inclusion Body MyositisMohammad Salajegheh

Initial Results from Single Subcutaneous Administration of ACE-031, a Form of the Soluble Activin Type IIB Receptor, in Healthy Postmenopausal VolunteersJasbir Seehra


2008 MSG Annual Meeting

The MSG held a meeting of clinical scientists on September 15-17, 2008 at Beaver Hollow, Java Center, NY, entitled “Experimental Therapeutics of Neuromuscular Disease.” The conference brought together translational and clinical scientists in a forum for discussion of current and novel therapies and drew speakers and participation from international experts with an interest in developing international collaborations among trainees and investigators focused on clinical trials. Specific to international collaboration many members of the TREAT-NMD consortium based in Europe attended the meeting, thereby fostering connections necessary to facilitate clinical trials in the rare diseases.

The agenda included two major sessions: (1) Novel designs and outcome measures in translational neuromuscular research and (2) scientific updates in basic science, methods and treatment strategies.

The meeting was sponsored by:

  • National Institutes of Health:
    • National Institute of Neurological Disorders and Stroke (NINDS)
    • Office of the Director (OD)
    • National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
  • Muscular Dystrophy Association
  • Acceleron Pharma

Presentations

The MSG received approval to post the following presentations online:

Ocular MGMichael Benatar

Sleuthing Targets for Disease in MuscleAndrew Engel

Clinical Investigation of Neurological Channelopathies (CINCH) LandmarksRobert C. Griggs

HYP HOPRobert C. Griggs

Clinical Trials: From Inception to ImplementationLaura Herbelin

Trial Implementation StrategiesCornelia Kamp

Clinical Materials Services Unit (CMSU)Cornelia Kamp

Iplex Treatment of Myotonic DystrophyRichard T. Moxley III

High Dose Ascorbic Acid to Treat CMT1AMichael Shy


MSG 2007 Annual Meeting

Through the funding of an NIH R13 award, the MSG held a meeting of clinical scientists on September 17-19, 2007, at Beaver Hollow, Java Center, NY. The program emphasized translational approaches to bringing molecular discoveries into well-designed clinical studies.

The agenda included two major sessions: (1) Novel designs and outcome measures in translational neuromuscular research and (2) scientific updates in basic science, methods and treatment strategies.


MSG 2006 Annual Meeting

Through the funding of an NIH R13 award, the MSG held a meeting of clinical scientists on May 31 through June 2, 2006 at Beaver Hollow, Java Center, NY. The program emphasized translational and experimental therapeutics research.

The agenda included two major sessions: (1) Translational bench-to-bedside presentations on topics including muscular dystrophy, neuromuscular junction disorders and motor neuron disorders and (2) Clinical trial methodology session including industry, FDA and academic perspectives.